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. Author manuscript; available in PMC: 2009 Jul 27.
Published in final edited form as: Clin Rev Allergy Immunol. 2008 Jun;34(3):352–355. doi: 10.1007/s12016-007-8044-z

Table 1.

Proportions of scleroderma patients and controls with skewed X-inactivation.

No. (%) observed with skewing
Degree of skewing (%) Present study (n=94) Previous study11 (n=55) Combined (n=149) Control (n=124)
+90 17(18.1%) 27(49.1%) 44 (29.5%) 3 (2.4%)
80-89 15(16.0%) 8 (14.5%) 23(15.4%) 7 (5.6%)
70-79 15(16.0%) 0 (0.0%) 15(10.1%) 22(17.7%)
60-69 24 (25.5%) 5(9.1%) 29(19.5%) 29 (23.4%)
50-59 23 (24.5%) 15(27.3%) 38 (25.5%) 63 (50.8%)

For comparison by χ2, P<0.0001(both >80% skewing and >90% skewing)