Table 2.
Summary of the discovered CTL epitope association rules.
| Data sets | ||||
| Association rules | 62-all | 44-non-CRFs | 18-CRFs * | Pseudo-set |
| Number of epitope associations with support >= 0.75 * & confidence >= 0.95 | 1961 | 1095 | 1867 | 1944 |
| Unique epitope associations# | ||||
| Associations with 2 epitopes $ | 46 | 48 | 45 | 46 |
| Associations with 3 epitopes | 217 | 166 | 71 | 217 |
| Associations with 4 epitopes | 153 | 102 | 59 | 151 |
| Associations with 5 epitopes | 59 | 26 | 27 | 58 |
| Associations with 6 epitopes | 9 | 2 | 7 | 9 |
| Associations with 7 epitopes | 0 | 0 | 1 | 0 |
| Total | 484 | 344 | 210 | 481 |
| Unique epitope associations with epitopes from only one gene | ||||
| Epitopes from Gag only | 9 | 12 | 3 | 9 |
| Epitopes from Pol only | 94 | 81 | 47 | 94 |
| Epitopes from Nef only | 0 | 0 | 0 | 0 |
| Total | 103 | 93 | 50 | 103 |
| Unique epitope associations with epitopes from two genes | ||||
| Gag-Pol | 329 | 234 | 145 | 326 |
| Pol-Nef | 26 | 11 | 7 | 26 |
| Nef-Gag | 3 | 1 | 1 | 3 |
| Total | 358 | 246 | 153 | 355 |
| Unique epitope associations with epitopes from all three genes (Gag-Pol-Nef) | 23 | 5 | 7 | 23 |
* Total number of associations includes all identified association rules that had a minimum support of 75% and 95% confidence. For CRFs, the support is 95%.
# "Unique" rules combine associations between the same epitopes into a single, "unique" rule regardless of the order of epitopes within a rule (i.e., A occurs with B and B occurs with A are considered the same "unique" rule).
$ i.e., association rules that involve two distinct CTL epitopes.