Table 1.

Approximate CPU times for the INM analysis of scorpion toxin at 15 temperatures on an ∼2 GHz CPU (see text for number of configurations)

Computation	CPU-time
Double-well filtering	300 days
Minimization for escape filtering	2 years
Escape filtering	3 years
Partial minimization (45 matrices)	10 days
Gradient minimization	10 days