Figure 4.

Early components of the amplificatory shift are shown with a faster C_m sampling rate. (A) C_m relaxations measured in the same cell in response to a voltage step from +50 mV to −150 mV. Top trace was sampled at 1.96 kHz and bottom trace (shifted down for visibility) was sampled at 196 Hz. Early components are evident with fast sampling. (B) Example of C_m relaxation (averaged traces, n = 9) in response to 20 ms voltage step from +50 to −150 mV at a C_m sampling frequency of 3.9 kHz. In this case a double exponential fit and stretched fit provide equally good fits as indicated by residuals. For six cells, τ₀: 0.57 ± 0.142 τ₁: 6.38 ± 1.22 ms; A₀: 1.61 ± 0.3, A₁: 1.7 ± 0.41 pF.