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. 2009 Jul 27;2009:305420. doi: 10.1155/2009/305420

Table 1.

List of miRNAs and their target gene involved in human breast cancer.

MicroRNA Targets Aberrant expression and roles References
MiR-21 BCL2, TPM1, PDCD4, PTEN Overexpressed and play oncogenic role [1417]
MiR-10b Homeobox D10 Down modulated, but associated with metastatic potential [20]
MiR-27a ZBTB10 Oncogenic role in breast cancer cells [21]
MiR-206 ERα Overexpressed [22, 23]
MiR-17-5p AIB1 Oncosuppressor in breast cell lines [24]
MiR-125a, miR-125b ERBB2, ERBB3 Down modulated and act as oncosuppressor [9, 25]
Let-7 RAS, HMGA2 Down modulated and reduced in BT-ICs [26]
MiR-205 HER3 Down modulated [27]