Figure 4. Genetic interaction and Cdc14 release profile of histone H3 methylase mutants combined with MEN mutants.
(A) Genetic interactions of set1Δ, dot1Δ, set2Δ, set1Δ dot1Δ, and set1Δ set2Δ mutations with the lte1Δ mutation. Strains were assayed as in Figure 2A. (B,C) The temporal profile of Cdc14 release from nucleolar sequestration is displayed for strains of the indicated genotypes. Time courses were performed as described in Figure 2C.