TABLE 3. iTRAQ Identification of Proteins Specifically Up-regulated by Egln1 Knockdown in VHL(−) Renal Carcinoma Cells.

Fold change in the protein level VHL(−)/Egln1kd cells vs. VHL(−) cells. 2-fold difference: above 2.112; 0.75-fold difference: above 1.848; 0.6-fold difference: above 1.690; 0.5-fold difference: above 1.584.

Protein	Function	Accession No.	Protein MW	Protein PI	Pep. Count	Total Ion Score	Fold Change
ATP5B	Mitochondrial ATP synthase, H+ transporting F1 complex beta subunit	gi\|89574029	51109.2	4.95	13	1104	1.7197
ATP5A	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	gi\|15030240	64238.8	9.07	8	670	1.9214
MRCL3	Myosin regulatory light chain MRCL3	gi\|5453740	21943.0	4.67	4	267	1.6127
SLC25A5	Solute carrier family 25, member 5	gi\|156071459	36289.6	9.71	4	253	2.1506
SLC25A6	Solute carrier family 25, memberA6	gi\|156071462	36159.5	9.76	4	247	2.2699
BASP1	Brain abundant, membrane attached signal protein 1	gi\|12653493	27363.4	4.67	3	200	1.5852
MYO1C	Myosin 1C	gi\|45751608	127386.6	9.48	3	184	1.5852
NUPL2	Nucleoporin 205kDa	gi\|57634534	240888.6	5.83	3	161	1.6515
NDUFA5	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5	gi\|47682777	15335.5	5.75	1	158	1.9214
MYO1B	Myosin-lb	gi\|68583739	147609	9.43	2	156	1.6402
ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	gi\|54696534	25884.5	10.00	1	123	2.4129
ATAD3A	ATPase family AAA domain-containing protein 3A	gi\|84028405	76656.5	9.08	2	115	1.8665
TOMM20	translocase of outer mitochondrial membrane 20 homolog	gi\|48145553	18002.9	8.80	1	113	1.8324
UQCRH	Ubiquinol-cytochrome c reductase hinge protein	gi\|83627705	11596.5	4.39	1	111	2.4716
SLC2A2	Glucose transporter glycoprotein	gi\|3387905	39584.4	7.59	2	89	1.7547
ATP5F1	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 precursor	gi\|21361565	31916.5	9.37	1	75	3.7311