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Indications for transplantation in PBC
| Indications |
| Symptom based |
| Intractable pruritus refractory to medical therapy |
| Hepatic encephalopathy |
| End-stage liver disease |
| Recurrent variceal haemorrhage |
| Episode of spontaneous bacterial peritonitis |
| Pulmonary hypertension |
| Hepato-pulmonary syndrome |
| Diuretic resistant ascites |
| Progressive osteopaenia |
| Muscle-wasting |
| Hepatoma (Milan criteria) |
| Biochemistry |
| Serum bilirubin > 150 μmol/L |
| Serum albumin < 25 g/L |
