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(A) The average structure of the inactive form of the WT RET kinase with M918 residue shown in CPK model. (B) A closeup of structural packing near the mutational site in the inactive WT RET kinase. (C) The average structure of the inactive form of the M918T RET kinase mutant with T918 residue shown in CPK model. (D) A closeup of structural packing near the mutational site in the inactive T918 RET kinase.
