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(A) The average structure of the inactive form of WT MET kinase with M1250 residue shown in CPK model. (B) A closeup of structural packing near the mutational site in the inactive WT MET kinase. (C) The average structure of the inactive form of M1250T MET kinase mutant with T1250 residue shown in CPK model. (D) A closeup of structural packing near the mutational site in the inactive T1250 MET kinase.
