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Pressure dependence of microtubule-based kinesin motility (mean ± SD, n = 5–82). (A) Reversible inhibition of sliding movement of kinesin motors. [ATP] = 1 mM. (B) Michaelis-Menten kinetics. (Inset) Fitted parameters (mean ± SD). (C) Pressure dependence of sliding velocity. [ATP] = 1 mM (solid circles) and 10 μM (open circles).
