Figure 5.

SMD simulation of C2A and C2B domains. Two snapshots of the extension C2AB (residues 140–414) pulled at a constant velocity of 0.001Å ps⁻¹ over 20 nm. The fixed atom was in residue 414 in C2B. The top structure represents the initial conformation of C2AB, and the bottom structure represents the conformation after 200 Å in the simulation. The red sphere corresponds to the fixed atom, and the green sphere and arrow correspond to the moving atom. The Ca⁺²-binding residues of C2A are highlighted as sticks. The Figure was rendered using VMD and Tachyon.