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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Exp Mol Pathol. 2009 Jan 20;86(3):151–164. doi: 10.1016/j.yexmp.2009.01.004

Figure 1. Strategies for the Therapeutic Use of Oligonucleotides.

Figure 1

Cartoon showing different approaches using oligonucleotides (oligos) as targeted therapeutic agents. G-rich oligonucleotides appear to function as aptamers to various proteins. In the case of AS1411, the target protein is believed to be nucleolin.