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Ureteric bud branching morphogenesis in the mouse. Ureteric bud (UB) emerges from the nephric duct on embryonic (E) day E10.5. Metanephros isolated on E11.5 from Hoxb7-GFP transgenic mouse embryo and grown ex vivo for 48 hours. Hoxb7 promoter directs expression of green fluorescent protein (GFP) to the UB. The number of branching structures increases progressively with time.
