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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: J Thorac Oncol. 2009 Apr;4(4):448–454. doi: 10.1097/JTO.0b013e31819c78fb

Figure 3. Effect on Matrigel invasion.

Figure 3

A) A549 cells were plated in the upper chamber of a transwell coated with Matrigel with DMSO or AZD0530 at 1 μM. After 48 hours, cells invading through the Matrigel were photographed. B) A549 and Calu-6 cells invading through the Matrigel were fixed, stained with 0.5% methylene blue and counted. Results presented as a percentage of the A549 DMSO control (±SEM of quadruplicate wells). C) A549 cells were incubated with AZD0530 at indicated doses for 24 hours, followed by FAK-immunoprecipitation and Western blotting for pY576-FAK and total FAK.

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