Figure 6. Inhibition of AKT and Bcl-xL.
A) Basal expression of pS473-AKT, AKT, Bcl-XL and Bcl-2 by Western blotting in a panel of lung cancer cell lines. B) A549 cells were incubated with increasing concentrations of PP2 for 24 hours, followed by Western blotting for pS473-AKT, AKT, Bcl-XL and Actin. C) A549 cells were incubated with AZD0530 for 24 hours at the doses indicated, followed by Western blotting for pS473-AKT, AKT, Bcl-XL and Actin.