Table 1.
Risk factors associated with HBV reactivation in HBsAg-positive patients treated with cytotoxic or immunosuppressive therapy, identified by multivariate analysis
| Author | Underlying diseases | Rate of HBV reactivation (%) | Risk factors |
|---|---|---|---|
| Yeo et al. [18] | HCC | 36 | Elevated serum ALT level |
| Lau et al. [20] | Lymphoma | 45 | Serum HBV DNA>105 copies/ml |
| Jang et al. [89] | HCC | 22 | Positive serum HBeAg |
| Nagamatsu et al. [58] | HCC | 24 | Positive serum HBeAg |
| Zhong et al. [90] | Various malignancies | 26 | Lymphoma/breast Ca, Anthracycline/steroid Serum HBV DNA>103 copies/ml |
| Hui et al. [83] | Lymphoma | 41 | High intrahepatic cccDNA |