Comparison of gene expression profiles in fetal and adult human livers. In fetal livers, CK-19 was expressed in ductal plate cells and parenchymal hepatoblasts, whereas CK-19 expression was restricted to bile ducts in the adult liver (panels on left). Albumin was expressed in fetal hepatoblasts and ductal plate cells (center panels), whereas α-fetoprotein was expressed in only parenchymal hepatoblasts and ductal plate cells (panels on right). Adult hepatocytes showed extensive albumin, but not α-fetoprotein staining. Original magnification, 400×, toluidine blue counterstain