Table 5.

Comparison between those patients who received adefovir and those who did not

	Administration of adefovir (n = 36)		No administration of adefovir (n = 24)		P
Age (years) mean ± SD	45.0 ± 10.5		41.3 ± 12.3		NS
Gender: male:female (%male)	29:7 (80.1%)		15:9 (62.5%)		NS
HBeAg-positive patients	25 (69.4%)		19 (79.2%)		NS
Alanine aminotransferase (IU/l)
Mean ± SD	148.7 ± 202.5		170.0 ± 239.6		NS
Serum HBV DNA (LGE/ml)
Mean ± SD	7.64 ± 1.03		6.91 ± 1.30		<0.05
YMDD mutation	YIDD	20	YIDD	13
	YVDD	8	YVDD	4
	YIDD + YVDD	3	YIDD + YVDD	0

HBeAg: Hepatitis B e antigen

NS: Not significant

YMDD mutation: YMDD motif of the HBV DNA polymerase

YIDD: Methionine to isoleucine

YVDD: Methioneine to valine