Table 3.
Multivariate Logistic Regression Analyses for Predicting the Probability of Excellent Pathologic Response After Neoadjuvant Chemotherapy With or Without the Continuous GGI
Variable | Analysis Without Continuous GGI |
Analysis With Continuous GGI |
||||
---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | |
Age, > 50 v ≤ 50 years | 0.88 | 0.47 to 1.64 | .692 | 0.94 | 0.50 to 1.77 | .839 |
ER status, positive v negative | 0.34 | 0.16 to 0.72 | .004 | 0.43 | 0.20 to 0.91 | .028 |
Nodal status, positive v negative | 0.35 | 0.17 to 0.72 | .005 | 0.32 | 0.16 to 0.68 | .003 |
Grade, 3 v 1 or 2 | 3.33 | 1.51 to 7.33 | .003 | 2.26 | 0.97 to 5.24 | .059 |
T stage, 2 or 3 v 1 | 0.85 | 0.43 to 1.67 | .635 | 0.81 | 0.40 to 1.62 | .550 |
Continuous GGI* | — | — | — | 1.86 | 1.15 to 3.00 | .011 |
NOTE. Likelihood ratio test for the comparison between the analysis with and without the GGI: P = .008 and χ2 = 6.93.
Abbreviations: GGI, genomic grade index; OR, odds ratio; ER, estrogen receptor.
GGI used as a continuous covariate.