Table A1.

Multivariate Logistic Regression Analyses for Predicting the Probability of Excellent Pathologic Response After Neoadjuvant Chemotherapy With or Without the Continuous GGI Including Ki67

Variable	Analysis Without GGI			Analysis With GGI*
	Odds Ratio	95% CI	P	Odds Ratio	95% CI	P
Age, > 50 v ≤ 50 years	0.88	0.47 to 1.64	.679	0.88	0.46 to 1.68	.709
ER status, positive v negative	0.34	0.16 to 0.72	.005	0.39	0.18 to 0.84	.016
Nodal status, positive v negative	0.35	0.17 to 0.72	.005	0.32	0.15 to 0.68	.003
Grade, 3 v 1 or 2	3.37	1.52 to 7.48	.003	2.22	0.95 to 5.16	.065
T stage, 2 or 3 v 1	0.85	0.43 to 1.67	.633	0.79	0.39 to 1.60	.517
Ki67, log2 transformed	0.94	0.53 to 1.67	.845	0.54	0.27 to 1.08	.082
Continuous GGI	—	—	—	2.37	1.36 to 4.16	.002

NOTE. Likelihood ratio test for the comparison between the analysis with and without the GGI: P = .002 and χ2 = 9.97.

Abbreviations: GGI, genomic grade index; ER, estrogen receptor.