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. 2009 Aug;175(2):605–615. doi: 10.2353/ajpath.2009.080991

Figure 10.

Figure 10

IGFBP-5 induces migration of mouse lung fibroblasts and splenocytes in an Egr-1-dependent manner. A: Primary mouse lung fibroblasts from wild-type and Egr-1 KO mice were used in migration assays with a vehicle control (veh) or recombinant IGFBP-5 (rBP5). B: Migration of lung fibroblasts from wild-type and Egr-1 KO mice. Data represent mean +SD of 15 independent fields. *P < 9.0 × 10−4, **P < 5.0 × 10−5, ***P < 0.05. C: Migration of splenocytes from wild-type and Egr-1 KO mice. Data represent mean + SD of six independent experiments. *P < 0.003, **P < 0.006.