Changes of hepatic Igf1r, Igf1, and Igf2 expression associated with cholestatic liver injury. Liver samples from Sham or BDL control mice were examined 3 or 21 days after surgery by RT-QPCR for expression of Igf1r (A), Igf1 (B), and Igf2 (C). Data were normalized to 18S rRNA and represent means ± SEM for 4 to 6 animals. *P < 0.05. NS, not significant.