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. 2009 Aug;175(2):668–684. doi: 10.2353/ajpath.2009.081126

Figure 2.

Figure 2

Magnetic resonance spectroscopy indicates hippocampal neuronal injury during acute TMEV infection of the CNS. Spectroscopic analysis of N-acetylaspartate (NAA) and creatine levels within a 27 μl voxel (D) containing the dorsomedial aspect of the hippocampus at 1 dpi (A) and 7 dpi (B) indicated a suppression of the NAA line relative to creatine. C: Quantitation of the ratio of NAA to creatine showed a 36% reduction consistent with neuronal injury in the hippocampus: t(4) = 6.181, P = 0.003 for 7 dpi vs 1 dpi by t-test.