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Acute infection with TMEV results in damage localized to the hippocampus. Histological analysis by H&E staining indicated focal tissue damage isolated to the pyramidal neurons in the CA1 subfield of the hippocampus (B) at 7 dpi. Pathology was never observed in CA1 in sham-infected mice (A). Arrowheads delineate CA1 in (A) and (B). Scale bar = 500 μm in (B) (also refers to A).
