Skip to main content
. 2009 Aug;175(2):891–902. doi: 10.2353/ajpath.2009.081115

Figure 5.

Figure 5

Inflammatory cytokine expression in mice treated with arginase inhibitor. Mice were pretreated with vehicle (Veh) or arginase inhibitor (BEC, 20 mg/kg, i.v.) 1 hour before LPS injection. 16 hours after LPS treatment, mice were sacrificed and retina samples were separated into single cell suspension and stained with A: TNF-α; B: VEGF; in combination with one of the following cell markers: GFAP for neuroglia, F4/80 for macrophage/microglia. The portion of positively stained cells in each cell type population was determined by flow cytometry (n = 3 experiments with pooled retinas). Mice without LPS treatment were served as control (Con). #P < 0.05 compared with control. *P < 0.05 compared with Veh+LPS.