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. 2002 Winter;7(4):201–204.

TABLE 2.

−3A/−4A (−138) endothelin-1 (ET-1) gene (6p21.3) polymorphism and allelic distribution in normotensive and hypertensive groups

Genotypes and alleles
3A3A 3A4AA 4A4A 3A 4A P
Hypertensive group (n=199) 101 84 14 0.696 0.304
  Men (n=112) 54 51 7 0.710 0.290
  Women (n=87) 47 33 7 0.730 0.270
Control group (n=181) 79 85 17 0.662 0.338 0.187
  Men (n=81) 36 38 7 0.679 0.321 0.295
  Women (n=100) 43 47 10 0.665 0.335 0.106