Table 2.
Odds Ratio (OR) of Prostate Cancer According to Quintile of Serum Retinol and Stage of Disease Progression at Diagnosis
| Serum Retinol | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Q11 | Q2 | Q3 | Q4 | Q5 | p-trend | ||||||
| Cases | OR (95% CI)4 | Cases | OR (95% CI)4 | Cases | OR (95% CI)4 | Cases | OR (95% CI)4 | Cases | OR (95% CI)5 | ||
| All Cases 2 | 155 | 1.00 | 154 | 0.97(0.71,1.34) | 124 | 0.77 (0.55,1.07) | 130 | 0.79 (0.57,1.10) | 129 | 0.80 (0.57,1.11) | 0.11 |
| Non-Aggressive 3 | 94 | 1.00 | 96 | 1.22 (0.84,1.79) | 71 | 0.86 (0.58,1.29) | 79 | 0.95 (0.64,1.41) | 83 | 0.97 (0.66,1.43) | 0.53 |
| Aggressive | 68 | 1.00 | 57 | 0.69 (0.44,1.07) | 52 | 0.64 (0.40,1.00) | 49 | 0.57 (0.36,0.91) | 43 | 0.58 (0.36,0.92) | 0.02 |
| Stage III & IV | 18 | 1.00 | 20 | 0.87 (0.42,1.79) | 19 | 0.83 (0.40,1.73) | 19 | 0.74 (0.35,1.56) | 14 | 0.69 (0.32,1.51) | 0.33 |
| Gleason Sum >=7 | 66 | 1.00 | 48 | 0.58 (0.37,0.92) | 42 | 0.50 (0.31,0.82) | 39 | 0.45 (0.27,0.73) | 39 | 0.52 (0.32,0.84) | 0.01 |
CI confidence interval
1
Reference category
2
Numbers of Non-Aggressive and Aggressive do not add up to All Cases due to missing information on stage or grade
3
Aggressive defined as Gleason Sum ≥7 or stage III or IV
4
Adjusted for age, time since initial screening, year of blood draw, and study center