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. Author manuscript; available in PMC: 2009 Jul 28.
Published in final edited form as: Cardiovasc Res. 2007 Mar 12;75(1):69–78. doi: 10.1016/j.cardiores.2007.03.002

Fig. 2. jSR alterations in CASQ2D307H (6-fold) myocytes.

Fig. 2

(A) In WT myocardium, the jSR cisternae are narrow, they contain a condensed form of CASQ2 and are closely apposed to wide T tubule profiles (T). (B,C) Most of the jSR cisternae in the mutant myocytes are quite similar to those in WT. (D–F) Alterations of jSR in mutant myocytes include a looser appearance of the CASQ2 in the lumen and an increase in width of the cisternae. The double arrows in A, E and F indicate the widening of terminal cisternae in TG compared to WT myocytes.