. Author manuscript; available in PMC: 2009 Jul 28.

Published in final edited form as: J Autoimmun. 2007 Jun 19;29(1):1–9. doi: 10.1016/j.jaut.2007.05.002

TABLE 1.

Lifetime Prevalence of 31 Autoimmune Diseases From two Reviews and among 5,472,032 persons in Denmark in 2001 per 1000 population

Disease	ICD8	ICD10	Number of “High” Comorbidities^$	Prior Studies^*	Number of Cases^†	Prevalence
Thyrotoxicosis	242.0	E05	1	11.51	34,434	6.29
Autoimmune Thyroiditis	245	E06.3	5	7.92^#	3,388	0.62
Insulin Dependent Diabetes	250.0	E10	6	1.92^£	51,783	9.46
Primary Adrenocortical Insufficiency	255.1	E27.1	7	0.14	983	0.18
Celiac Disease	269.0	K90.0	9	9.9^a	2,722	0.50
Pernicious Anemia	281.0	D51.0	8	1.51	2,947	0.54
Autoimmune Haemolytic Anemia	283.9	D59.1	11	--	912	0.17
Idiopathic Thrombocytopenic Purpura	287.19	D69.3	3	--	3,940	0.72
Multiple Sclerosis	340.0	G35	4	0.58	9,961	1.82
Guillain Barre Syndrome	354.0	G61.0	6	∼0.38^b	3,926	0.72
Iridocyclitis	366.0	H20	5	0.02	8,126	1.49
Wegener’s Granulomatosis	446.29	M31.3	6	0.03	568	0.10
Crohn’s Disease	563.0	K50	2	0.54^c	12,309	2.25
Ulcerative Colitis	563.19	K51	5	1.61^d-	20,669	3.78
Primary Biliary Cirrhosis	571.90	K74.3	10	0.04	666	0.12
Chronic Hepatitis, n.e.c.	571.93	K73	11	0.004	2,472	0.45
Interstitial Cystitis	595.0	N30.1	3	3.0^e	39,496	7.22
Endometriosis	625.3	N80	0	--	26,882	4.91
Pemphigoid	693	L12.0	5	--	895	0.16
Pemphigus	694		2	--	195	0.04
Psoriasis vulgaris	696	L40.0	6	15.0^f	10,788	1.97
Alopecia Areata	704.00	L63	5	17.0^g--	1,172	0.21
Vitiligo	709.0-19	L80	10	4.0	1,576	0.29
Seropositive Rheumatoid Arthritis	712	M05	10	8.6^¤	20,831	3.81
Dermatopolymyositis	716	M33	12	0.05	949	0.17
Myositis	717.90	M60	4	--	45,051	8.23
Polymyalgia Rheumatica	717.99	M31.5	3	6.1^h	6,136	1.12
Myasthenia Gravis	733.09	G70.0^&	6	0.05	977	0.18
Systemic Sclerosis	734.0	M34	9	0.04	1,257	0.23
Systemic Lupus Erythematosis	734.19	M32.1^@	14	0.24	1,732	0.32
Sjogren’s Sydrome	734.90	M35.0	14	0.14	2,615	0.48

Notes for Table 1

Including G70.0, G70.2, G70.8 and G70.9

Including M32.1, M32.8 and M32.9.

A “high” comorbidity is defined in the text.

Prior studies from review of Jacobson et al, 1997, as updated by Cooper et al, 2003.

Ages > 19.

^£

Ages < 20.

^¤

Adult

^†

The specific autoimmune diseases are not mutually exclusive: that is, a person may have more than one autoimmune disease.

(39)

(40). Incidence was estimated in that study as 1.26/100,000/year. Assuming little mortality and 30 years of risk, the prevalence was estimated to be 37.8.

(41)

(42)

(43)

(44)

(45)

(46)