RGS11 but not RGS7 mutation delays the b-wave of the photopic ERG. ERG responses for representative subjects to a range of increasing stimulus energies, from bottom to top, recorded for a rod suppressing background of 1.8 log sc td. The top most traces represent averaged ERG response for a high-energy flash of 2.3 log sc td s (n = 4 for RGS7 mutants and their littermate controls; n = 9 for RGS11and n = 6 for RGS11 littermate controls). Gray traces (left), RGS7 mutants; gray traces (right), RGS11mutants; black traces, heterozygous littermate control; dotted traces, ±SEM. Inset top right corner shows the averaged b-wave traces after filtering OPs.