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. Author manuscript; available in PMC: 2010 Jan 16.
Published in final edited form as: Oncogene. 2009 May 18;28(28):2556–2568. doi: 10.1038/onc.2009.118

Figure 6. Effect of ROS scavengers on 15d-PGJ2 induced cytoplasmic vacuolation, cell death, ER stress and LC3 induction and processing.

Figure 6

A. Effect of ROS scavengers, NAC, NMPG, TEMPOL and Trolox on 15d-PGJ2 induced cytoplasmic vacuolation as revealed by phase contrast images. B. Effect of ROS scavengers on cytotoxic effects of 15d-PGJ2 as measured by clonogenic assay. C. Immunoblots showing the effect of NAC, NMPG, TEMPOL and Trolox on the expression of ER stress markers Bip, Chop and processing and induction of LC3. D. Effect of above ROS scavengers on the accumulation of ubiquitinated proteins as revealed by western blotting with anti-ubiquitin antibody.