Table 3.
Stratum | DDE tertile (ng/g wet weight) | No. per tertile | Incident cases (no.) | Person-years of follow-up | Incidence/1,000 person-years (no.) | Crude IRR per one-tertile increase (95% CI) | p-Value for trend | Adjusted IRR per one-tertile increasea (95% CI) | p-Value for trend |
---|---|---|---|---|---|---|---|---|---|
BMI (kg/m2) | |||||||||
17–25 | < LOD to 2.2 | 64 | 0 | 580 | 0 | 3.5 (0.5–25.8) | 0.26 | 3.0 (0.4–26.2) | 0.33 |
2.3–5.3 | 43 | 1 | 385 | 2.6 | |||||
5.4–49.2 | 28 | 1 | 243 | 4.1 | |||||
25–29 | < LOD to 2.2 | 48 | 2 | 364 | 5.5 | 1.6 (0.6–4.3) | 0.31 | 1.7 (0.6–4.9) | 0.30 |
2.3–5.3 | 67 | 2 | 553 | 3.6 | |||||
5.4–49.2 | 43 | 4 | 331 | 12.1 | |||||
29–48 | < LOD to 2.2 | 41 | 0 | 381 | 0 | 2.2 (1.2–4.1) | 0.01 | 2.2 (1.1–4.3) | 0.02 |
2.3–5.3 | 52 | 9 | 398 | 22.6 | |||||
5.4–49.2 | 85 | 17 | 712 | 23.8 | |||||
Age (years) | |||||||||
25–44 | < LOD to 2.2 | 83 | 1 | 752 | 1.3 | 1.8 (0.5–6.0) | 0.33 | 1.5 (0.5–5.0) | 0.48 |
2.3–5.3 | 48 | 2 | 398 | 5.0 | |||||
5.4–49.2 | 26 | 1 | 240 | 4.2 | |||||
44–52 | < LOD to 2.2 | 46 | 1 | 370 | 2.7 | 2.0 (0.9–4.5) | 0.08 | 1.5 (0.7–3.3) | 0.26 |
2.3–5.3 | 60 | 5 | 459 | 10.9 | |||||
5.4–49.2 | 51 | 6 | 396 | 15.2 | |||||
52–76 | < LOD to 2.2 | 24 | 0 | 204 | 0 | 2.9 (1.2–7.1) | 0.02 | 2.6 (1.0–6.3) | 0.04 |
2.3–5.3 | 54 | 5 | 480 | 10.4 | |||||
5.4–49.2 | 79 | 15 | 650 | 23.1 |
IRR from proportional hazards model adjusted for age, sex, and BMI.