Table 3. The allelic frequencies and associations between reduced sperm counts and common polymorphisms in the MTRR gene.

Gene	SNP	AA substitution	Genotype	Cases				Controls		Odds Ratio (95%CI)		Chi2		p value
				Azoospermic		Oligozoospermic
				n	%	n	%	n	%	Azoospermic	Oligozoospermic	Azoo	Oligo	Azoo	Oligo
MTRR	c.66A>G	p.122M	GG	19	28.79	61	35.26	42	37.84
			AG	39	59.09	93	53.76	57	51.35	1.512 (0.768–2.978)	1.123 (0.672–1.876)	1.438	0.198	0.2304	0.6566
			AA	8	12.12	19	10.98	12	10.81	1.474 (0.518–4.195)	1.090 (0.479–2.481)	0.531	0.042	0.4661	0.837
			AG+AA	47	71.21	112	64.74	69	62.16	1.506 (0.781–2.904)	1.118 (0.682–1.833)	1.501	0.194	0.2205	0.6593
			A allele frequency	55	41.67	131	37.86	81	36.49	1.501 (0.791–2.850)	1.114 (0.689–1.802)	1.551	0.192	0.213	0.6611
	c.524C>T	p.S175L	CC	29	41.43	61	34.08	35	31.53
			CT	30	42.86	78	43.57	60	54.05	0.603 (0.312–1.166)	0.746 (0.437–1.274)	2.271	1.157	0.1318	0.2821
			TT	11	15.71	40	22.35	16	14.42	0.830 (0.333–2.066)	1.434 (0.703–2.927)	0.161	0.987	0.6881	0.3205
			CT+TT	41	58.57	118	65.92	76	68.47	0.651 (0.344–1.212)	0.891 (0.537–1.478)	1.84	0.201	0.175	0.6542
			T allele Frequency	52	37.14	158	44.13	92	41.44	0.682 (0.375–1.240)	0.985 (0.604–1.606)	1.578	0.003	0.2091	0.9529