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. 2009 May-Jun;2(3):223–224. doi: 10.4161/cib.2.3.8073

Figure 1.

Figure 1

Penetratin induced tubulation in heterogeneous GUVs. (A) PC/SM/Chol/Di-Q (60/20/20/1) GUV showing the fluorescent liquid disordered domain (fluorescent Di-Q is a marker of liquid disordered domains), and a dark non fluorescent liquid ordered domain in the top of the GUV. The fluorescent tubes inside indicate that Penetratin is able to induce invaginations of membrane disordered domains. (B) PC/SM/Chol/GM1 (60/20/20/1) GUV showing the dark non fluorescent liquid disordered domain, and three fluorescent liquid ordered domains. The fluorescence from rhodamine-labelled cholera toxin binds specifically to the liquid ordered lipid marker GM1. The fluorescent tubes inside indicate that Penetratin is able to induce invaginations containing cholera toxin associated membrane ordered domains.