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Virologic and clinical differences between HBV subgenotypes B1 and B2
| B1 | B2 | |
|---|---|---|
| Positivity of HBeAg | Lower | Higher |
| Precore stop codon mutation | More | Less |
| Basal core promoter mutation | Less | More |
| Risk of hepatocellular carcinoma | Lower | Higher |
Abbreviations: B1, HBV genotype B without recombination with genotype C (G-1838); B2, HBV genotype B and C recombinant (A-1838).
