Table 2.
YEARS |
POPULATION (Reviewed file records/Selected patients) |
CASES OF HYPOSPADIAS | PREVALENCE | |
Our data | 2001–2004 (Italy) |
78228 | 234 | 3.066 ± 0.99 (per 1000 live births) |
Pierik et al, 2002 (Hum Reprod) |
1998–2000 (Olanda) |
7292 | 53 | 3.8 (per 1000 live births) |
Martti Olavi Aho et al, 2003 (Envir Res) |
1970–1986 (Finlandia) |
2164720 | 6,144 | 2.03–3.28 (per 1000 boys) |
Bianca et al, 2003 (Reprod Toxicol) |
1991–1998 (Sicilia, Italia) |
1323 (Augusta) 3243 (Vittoria) |
16 (Augusta) 24 (Vittoria) |
12.1 (Augusta) 7.4 (Vittoria) (per 1000 boys) |
Ahmed et al, 2004 (Arch Dis Child-Fetal Neon Ed) |
1988–1997 (Scozia) |
611849 | 2816 ** | 4.6 ** (per 1000 live births) |
Porter et al, 2005 (Pediatrics) |
1987–2002 (Washington State, USA) |
2155 | 4.6 (year 1987) 5.0 (year 2002) (per 1000 live births) |
* Data referred to SGA (Small for Gestational Age) newborns in NICU
** Data referred to genital abnormalities (hypospadias = 73%)
*** Data referred to hypospadias and epispadias