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. 2009 May 26;27(21):3437–3444. doi: 10.1200/JCO.2008.18.9068

Table 6.

HRs for Disease-Free and Overall Survival for One-Unit Increases in lnCRP and lnSAA, Stratified by Joint ER/PR Status (localized and regional stage disease only)

Survival ER Positive/PR Positive
ER Negative/PR Negative
ER Negative/PR Positive
ER Positive/PR Negative
No. of Events No. of Participants HR 95% CI No. of Events No. of Participants HR 95% CI No. of Events No. of Participants HR 95% CI No. of Events No. of Participants HR 95% CI
Overall survival
    lnCRP 41 302 1.39 1.05 to 1.86 14 88 2.01 0.96 to 4.02 2 16 * * 7 62 * *
    lnSAA 41 302 1.89 1.30 to 2.74 14 88 2.84 1.03 to 7.86 2 16 * * 7 62 * *
Disease-free survival
    lnCRP 36 299 0.98 0.69 to 1.39 14 87 1.49 0.71 to 3.13 2 16 * * 9 61 * *
    lnSAA 36 299 1.36 0.83 to 2.15 14 87 2.09 0.81 to 5.39 2 16 * * 9 61 * *

NOTE. HRs were adjusted for age (continuous), disease stage, race/study site, body mass index (continuous), and comorbidities (histories of heart failure and myocardial infarction.

Abbreviations: HR, hazard ratio; ER, estrogen receptor; PR, progesterone receptor.

*

There were too few events for regression to converge.