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. 2009 May 26;27(21):3540–3546. doi: 10.1200/JCO.2008.20.8793

Table 2.

Toxicity Comparisons

Toxicity Trial
P
FACS (n = 148)
LC00-03 (n = 197)
S0003 (n = 184)
No. % No. % No. %
Neutropenia grades 3-4 130 88 137 70 70 38 < .0001
Febrile neutropenia grades 3-4 27 18 24 12 4 2 < .0001
Thrombocytopenia grades 3-4 16 11 14 7 12 6.5 .31
Anemia grades 3-4 22 15 16 8 12 7 .03
Neuropathy grades 2-4 25 17 32 16 30 16 .99

Abbreviation: FACS, four-arm cooperative study.