Table 2.
Toxicity | Trial |
P | |||||
---|---|---|---|---|---|---|---|
FACS (n = 148) |
LC00-03 (n = 197) |
S0003 (n = 184) |
|||||
No. | % | No. | % | No. | % | ||
Neutropenia grades 3-4 | 130 | 88 | 137 | 70 | 70 | 38 | < .0001 |
Febrile neutropenia grades 3-4 | 27 | 18 | 24 | 12 | 4 | 2 | < .0001 |
Thrombocytopenia grades 3-4 | 16 | 11 | 14 | 7 | 12 | 6.5 | .31 |
Anemia grades 3-4 | 22 | 15 | 16 | 8 | 12 | 7 | .03 |
Neuropathy grades 2-4 | 25 | 17 | 32 | 16 | 30 | 16 | .99 |
Abbreviation: FACS, four-arm cooperative study.