Skip to main content
. 2009 Aug;23(8):2425–2437. doi: 10.1096/fj.09-131128

Figure 7.

Figure 7.

SOCE and STIM1/Orai1 protein levels are increased in proliferative migratory VSMCs. A, B) Thapsigargin (TG) (2 μM) activates a much bigger SOCE in synthetic VSMCs (Synth.VSMC; n=154) than in quiescent freshly dispersed VSMCs (Quiesc.VSMC; n=98). Traces are averages from 25 to 30 cells and are representative of 6 independent experiments, each analyzing 21–35 cells. C) Synthetic VSMCs express higher levels of STIM1 protein compared with quiescent freshly isolated VSMCs. D) Similar results were seen in regard to Orai1 expression. Western blotting data are representative of 4 independent experiments. RBL mast cells were used as controls for STIM1 protein expression.