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MnSOD overexpression increased levels of MnSOD and catalase and decreased oxidative stress. A, B) Western blots of MnSOD (A) and catalase (B). Densitometric values are normalized to β-actin. MnSOD and catalase protein levels were increased in Tg19959-MnSOD mice compared to Tg19959 littermates. C) Western blots of brain protein carbonyl levels. Densitometric values are normalized to β-actin. MnSOD overexpression decreased oxidative stress in Tg19959 mice. *P < 0.05.
