Table 1.
Characteristics of patients with acute myocardial infarction (AMI) according to the development of in-hospital stroke (Worcester Heart Attack Study).
| Stroke | |||
|---|---|---|---|
| Characteristic | Present (n=132) |
Absent (n=9,088) |
p-value |
| Age (mean, yrs) | 75.5 | 69.1 | <0.001 |
| Female (%) | 60.6 | 41.9 | <0.001 |
| Medical history (%) | |||
| Angina pectoris | 19.7 | 24.0 | 0.25 |
| Diabetes mellitus | 26.5 | 28.2 | 0.37 |
| Hypertension | 67.4 | 59.6 | 0.07 |
| Heart failure | 22.0 | 18.8 | 0.35 |
| Atrial fibrillation | 16.4 | 9.8 | 0.01 |
| Delay time to hospital (median, hours) | 2.4 | 2.0 | 0.24 |
| Length of hospital stay (median, days) | 6.0 | 8.5 | <0.001 |
| Do not resuscitate order (%) | 46.0 | 19.3 | <0.001 |
| Physiologic findings at admission (mean) | |||
| Hematocrit (%) (n=5540) | 38.7 | 40.2 | <0.01 |
| Glucose (mg/dl) (n=5478) | 188.1 | 182.0 | 0.53 |
| Total Cholesterol (mg/dl) (n=5211) | 185.3 | 199.9 | <0.01 |
| Systolic BP (mmHg) (n=4407) | 151 | 142 | <.05 |
| Diastolic BP (mmHg) (n=4258) | 81 | 77 | 0.18 |
| Peak Systolic BP during hospital stay (n=1796) | 173 | 158 | <0.05 |
| Peak Diastolic BP during hospital stay (n=1795) | 95 | 88 | <0.05 |
| Heart rate (bpm) (n=9065) | 93.8 (27.5) | 85.8 (23.9) | <0.01 |
| Estimated Glomerular | 54.4 (25.0) | 62.1 (28.7) | 0.01 |
| Filtration Rate (GFR) (ml/min per 1.73 m2) (n=5506) | |||
| GFR | |||
| ≤30 | 17.2 | 11.0 | |
| 30–59 | 43.0 | 34.6 | |
| ≥ 60 | 39.8 | 54.4 | 0.01 |
| AMI characteristics (%) | |||
| Initial | 59.1 | 67.0 | 0.06 |
| Q-wave | 32.6 | 35.6 | 0.47 |
| Anterior | 28.0 | 27.6 | 0.92 |
| Clinical complications (%) | |||
| Atrial fibrillation | 34.8 | 16.7 | <0.001 |
| Heart failure | 40.9 | 36.3 | 0.28 |
| Cardiogenic shock | 6.1 | 6.4 | 0.88 |
| Intervention procedures | |||
| Cardiac catherization | 28.0 | 41.4 | p<.01 |
| Percutaneous coronary intervention | 10.6 | 21.0 | p<.01 |
| Coronary artery bypass surgery | 4.6 | 4.7 | 0.94 |