Table 1.
Advantages and Disadvantages of Albumin Elimination versus Serum Fractionation.
| Techniques | Advantages | Disadvantages | |
|---|---|---|---|
| Albumin Elimination Techniques | Cibacron Blue F3GA | - Fast | - Loss of proteins bound to albumin |
| Antibody-Based Albumin Elimination | - Does not require specialized instrumentation | ||
| Serum Fractionation Techniques | Anion Exchange Chromatography | - High Recovery Rate | |
| Reversed-Phased High Performance Liquid Chromatography | - Can be coupled with other separation techniques | - Requires specialized Instrumentation | |
| Size Exclusion Chromatography | - Can be optimized to fractionate the serum sample into many fractions each enriched with target proteins | - Time consuming |