Table 1.
Comparison of clinicopathologic parameters between hepatocellular carcinoma with and without cirrhosis.
| Parameters | HCC-C | HCC-NC | p value* |
|---|---|---|---|
| Age | 0.707 | ||
| < 50 yrs | 6 | 4 | |
| >50 yrs | 14 | 16 | |
| Gender | 0.695 | ||
| Male | 15 | 17 | |
| Female | 5 | 3 | |
| Background liver disease | 0.002 | ||
| Hepatitis B | 8 | 2 | |
| Hepatitis C | 7 | 1 | |
| Non-specific hepatitis | 0 | 4 | |
| Alcoholic steatohepatitis | 3 | 5 | |
| None | 2 | 8 | |
| Histology type | 0.231 | ||
| Classic | 20 | 17 | |
| Fibrolamellar | 0 | 2 | |
| Sclerosing | 0 | 1 | |
| Tumor size | 0.200 | ||
| <5 cm | 11 | 6 | |
| >5 cm | 9 | 14 | |
| Tumor multiplicity | 1.000 | ||
| Solitary | 14 | 13 | |
| Multiple | 6 | 7 | |
| Tumor Grade (WHO) | 0.381 | ||
| I | 0 | 2 | |
| II | 17 | 14 | |
| III | 3 | 4 | |
| IV | 0 | 0 | |
| Lymphvascular invasion | 0.523 | ||
| Present | 7 | 10 | |
| Absent | 13 | 10 | |
| Tumor Stage | 0.875 | ||
| I | 10 | 10 | |
| II | 4 | 3 | |
| III | 3 | 5 | |
| IV | 3 | 2 | |
| Surgical margin | all negative | all negative | |
| 3 N/A | 4N/A |
HCC-C: hepatocellular carcinoma with cirrhosis; HCC-NC: hepatocellular carcinoma without cirrhosis.
*
Fisher’s exact test and chi-square analysis.