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. 2009 Apr 2;150(8):3709–3716. doi: 10.1210/en.2008-1721

Figure 1.

Figure 1

Enhanced sensitivity in females and CRFR2-deficient mice after acute citalopram administration in the tail suspension test. Citalopram (CIT) treatment decreased immobile time (A) in male R2KO and female mice relative to vehicle-treated mice (VEH) and increased latency (B) to first bout of immobility in female R2KO. A main effect of drug was detected to decrease immobility (P < 0.01) and increase latency (P < 0.01). Data are presented as mean ± sem. *, Significant genotype effect, P < 0.05; #, significant citalopram effect, P < 0.05; ##, P < 0.01.