Table V.
Joint effect of chromosome 9p-short and 9p-long telomere length on breast cancer risk
| 9p-short | 9p-long | Cases/controls | OR (95% CI) |
| All subjects | |||
| Longa | Longa | 30/53 | 1.00 |
| Short | Long | 24/28 | 2.71 (1.45–5.04) |
| Long | Short | 11/28 | 1.73 (0.85–3.54) |
| Short | Short | 75/50 | 3.97 (1.71–9.19) |
| Premenopausal women | |||
| Long | Long | 13/25 | 1.00 |
| Short | Long | 8/11 | 3.05 (1.20–7.78) |
| Long | Short | 4/13 | 2.44 (0.73–8.24) |
| Short | Short | 31/18 | 5.49 (1.46–20.7) |
| Postmenopausal women | |||
| Long | Long | 16/27 | 1.00 |
| Short | Long | 15/17 | 2.44 (1.04–5.71) |
| Long | Short | 6/15 | 1.39 (0.56–3.45) |
| Short | Short | 38/32 | 3.25 (1.08–9.82) |
ORs were adjusted for age as continuous, race, smoking status (never/ever), alcohol use (never/ever), education, family history of cancer (no/yes), hormone replacement therapy (no/yes), history of pregnancy (no/yes), menopausal status (when appropriate) and physical activity in teens (no/yes). No significant interactions between 9p-short and 9p-long were detected.
a
Chromosome 9p-short and 9p-long RTL were dichotomized by the median value in controls.