Table 2.

 Colposcopic impression and histological* outcome of initial colposcopy examination and related procedures, by trial arm (cross sectional analysis)

	Biopsy and recall			Immediate large loop excision
	No (% of those in arm)	% of those with abnormal transformation zone		No (% of those in arm)	% of those with abnormal transformation zone
Total women randomised	1000 (100)	—		983 (100)	—
Normal transformation zone†‡	397 (40)	—		482 (49)	—
Abnormal transformation zone§
Total	603 (60)	100		501 (51)	100
No CIN	269 (27)	45		156 (16)	31
CIN grade I	168 (17)	28		140 (14)	28
CIN grade II or worse¶	160 (16)	27		202 (21)	40
CIN grade II	77	—		100	—
CIN grade III or worse¶	83	—		102	—
Other**	6 (0.6)	1		3 (0.3)	0.6

CIN=cervical intraepithelial neoplasia.

*Represents most severe histology recorded after initial colposcopy (that is, for women in whom biopsy and large loop excision results did not correspond, most severe has been recorded).

†No abnormal transformation zone on colposcopy; women did not have any further procedures at this time.

‡Biopsy and recall figure includes 396 women with normal transformation zone on initial colposcopy, plus one woman originally found to have abnormal transformation zone who returned for treatment and at repeat colposcopy had normal transformation zone; immediate large loop excision figure includes 479 women with normal transformation zone at initial colposcopy, plus three women with abnormal transformation zone who were not treated immediately and, at repeat colposcopy, were found to have normal transformation zone.

§Abnormal transformation zone at colposcopy and women went on to receive intervention assigned by randomisation.

¶Three women had disease worse than CIN III, one in biopsy and recall arm and two in immediate large loop excision arm.

**Includes three women with inadequate histology (biopsy and recall arm), and six with no histology (three in each arm).