Ribbon drawing of the structure of full-length eIF4A. The amino- and
carboxyl-terminal domains are colored silver and gold, respectively;
the 11-residue linker connecting them is colored black. The conserved
amino-terminal motifs are colored as follows: motif I, Walker A motif
ASQSGTGKT, residues 65–72, blue; motif Ia, PTRELA, residues 97–102,
yellow; GG, residues 125–126, orange; TPGR, residues 145–148, pink;
motif II, Walker B motif DEAD, residues 169–172, red; motif III, SAT,
residues 200–202, green. The conserved carboxyl-terminal motifs are
colored as described in Fig. 1A.