Figure 7. A non-TASK, pH-sensitive background K⁺ channel.

A, channels recorded from cell-attached patches with membrane potential of +60 mV and −60 mV in bath and pipette solutions containing 140 mm KCl. B, current–voltage relationship. C, channel current was recorded in outside-out patch at different extracellular pH. D, channel activity observed at pH 7.3 was taken as 1.0, and the relative activity recorded at different pH values is plotted. Each bar is the mean ±s.d. of 4 determinations. Significance from the control value obtained at 7.3 is denoted by an asterisk (P < 0.05).