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. 2009 Jul 10;106(30):12224–12229. doi: 10.1073/pnas.0900406106

Fig. 5.

Fig. 5.

n 4(t) is plotted over an interval of time for output trajectories obtained with REM (upper trace, shifted for clarity) and RENS (lower trace). The 2 traces represent roughly the same number of attempted replica exchanges (≈ 1700) but reveal substantially different acceptance rates.